Dephosphorylation of Y685-VE-Cadherin Involved in Pulmonary Microvascular Endothelial Barrier Injury Induced by Angiotensin II

Figure 2

After establishing of acute lung injury model though minipumping of AngII, obvious edema was noticed in the pulmonary tissues in the AngII group, together with infiltration of neutrophils (MPO) and macrophages (CD68). However, after administration of PP2, no obvious changes were noticed in the infiltration of neutrophils and macrophages, as well as pulmonary edema compared with the AngII group. HE staining and immunohistochemistry images were observed under a magnification of 200x and 400x, respectively.