Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2016, Article ID 8970291, 9 pages
http://dx.doi.org/10.1155/2016/8970291
Research Article

Pretransplant Immune- and Apoptosis-Related Gene Expression Is Associated with Kidney Allograft Function

1Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, 52-129 Wrocław, Poland
2Department of Vascular, General and Transplant Surgery, Wroclaw Medical University, 52-129 Wrocław, Poland
3Department of Histology and Embryology, Wroclaw Medical University, 50-368 Wrocław, Poland

Received 29 February 2016; Revised 22 April 2016; Accepted 9 May 2016

Academic Editor: Simi Ali

Copyright © 2016 Dorota Kamińska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. D. Vaziri, M. V. Pahl, A. Crum, and K. Norris, “Effect of uremia on structure and function of immune system,” Journal of Renal Nutrition, vol. 22, no. 1, pp. 149–156, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. R. A. Zager, A. C. M. Johnson, and S. Lund, “Uremia impacts renal inflammatory cytokine gene expression in the setting of experimental acute kidney injury,” American Journal of Physiology—Renal Physiology, vol. 297, no. 4, pp. F961–F970, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Stompór, M. Pasowicz, W. Sułowicz et al., “An association between coronary artery calcification score, lipid profile, and selected markers of chronic inflammation in ESRD patients treated with peritoneal dialysis,” American Journal of Kidney Diseases, vol. 41, no. 1, pp. 203–211, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Z. Molnar, C. P. Kovesdy, S. Bunnapradist et al., “Associations of pretransplant serum albumin with post-transplant outcomes in kidney transplant recipients,” American Journal of Transplantation, vol. 11, no. 5, pp. 1006–1015, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. A. Roshdy, M. M. El-Khatib, M. N. Rizk, and A. M. El-Shehaby, “CRP and acute renal rejection: a marker to the point,” International Urology and Nephrology, vol. 44, no. 4, pp. 1251–1255, 2012. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Lessan-Pezeshki, A. Amirzargar, A. Fathi et al., “Value of pretransplantation cytokine profiles for predicting acute rejection in renal transplant recipients,” Transplantation Proceedings, vol. 37, no. 7, pp. 2982–2984, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Ghafari, K. Makhdoomi, P. Ahmadpour, A. T. Afshari, S. S. Lak, and L. Fakhri, “Serum T-lymphocyte cytokines cannot predict early acute rejection in renal transplantation,” Transplantation Proceedings, vol. 39, no. 4, pp. 958–961, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. K. W. Kim, B. H. Chung, E. J. Jeon et al., “B cell-associated immune profiles in patients with end-stage renal disease (ESRD),” Experimental and Molecular Medicine, vol. 44, no. 8, pp. 465–472, 2012. View at Publisher · View at Google Scholar · View at Scopus
  9. S. Kato, M. Chmielewski, H. Honda et al., “Aspects of immune dysfunction in end-stage renal disease,” Clinical Journal of the American Society of Nephrology, vol. 3, no. 5, pp. 1526–1533, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. P. C. Lee and M. Ozawa, “Reappraisal of HLA antibody analysis and crossmatching in kidney transplantation,” Clinical Transplantation, pp. 219–226, 2007. View at Google Scholar
  11. O. Bestard, J. M. Cruzado, M. Lucia et al., “Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation,” Kidney International, vol. 84, no. 6, pp. 1226–1236, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. K. Koscielska-Kasprzak, D. Drulis-Fajdasz, D. Kaminska et al., “Pretransplantation cellular alloreactivity is predictive of acute graft rejection and 1-year graft function in kidney transplant recipients,” Transplantation Proceedings, vol. 41, no. 8, pp. 3006–3008, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Sadeghi, V. Daniel, R. Weimer, M. Wiesel, O. Hergesell, and G. Opelz, “Pre-transplant Th1 and post-transplant Th2 cytokine patterns are associated with early acute rejection in renal transplant recipients,” Clinical Transplantation, vol. 17, no. 2, pp. 151–157, 2003. View at Publisher · View at Google Scholar · View at Scopus
  14. İ. Berber, B. Yiğit, G. Işıtmangil et al., “Evaluation of pretransplant serum cytokine levels in renal transplant recipients,” Transplantation Proceedings, vol. 40, no. 1, pp. 92–93, 2008. View at Publisher · View at Google Scholar
  15. M. Sadeghi, V. Daniel, C. Naujokat, A. Mehrabi, and G. Opelz, “Association of high pretransplant sIL-6R plasma levels with acute tubular necrosis in kidney graft recipients,” Transplantation, vol. 81, no. 12, pp. 1716–1724, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. J. T. Fitzgerald, J. R. Johnson, and R. V. Perez, “Pre-transplant elevations of interleukin-12 and interleukin-10 are associated with acute rejection after renal transplantation,” Clinical Transplantation, vol. 18, no. 4, pp. 434–439, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. G. K. Chin, C. L. Adams, B. S. Carey, S. Shaw, W.-Y. Tse, and E. R. Kaminski, “The value of serum neopterin, interferon-gamma levels and interleukin-12B polymorphisms in predicting acute renal allograft rejection,” Clinical and Experimental Immunology, vol. 152, no. 2, pp. 239–244, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. J. Sellarés, D. G. de Freitas, M. Mengel et al., “Understanding the causes of kidney transplant failure: the dominant role of antibody-mediated rejection and nonadherence,” American Journal of Transplantation, vol. 12, no. 2, pp. 388–399, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. M. Karczewski, J. Karczewski, B. Poniedzialek, K. Wiktorowicz, M. Smietanska, and M. Glyda, “Distinct cytokine patterns in different states of kidney allograft function,” Transplantation Proceedings, vol. 41, no. 10, pp. 4147–4149, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. E. Dounousi, E. Koliousi, A. Papagianni et al., “Mononuclear leukocyte apoptosis and inflammatory markers in patients with chronic kidney disease,” American Journal of Nephrology, vol. 36, no. 6, pp. 531–536, 2012. View at Publisher · View at Google Scholar · View at Scopus
  21. D. Kaminska, K. Koscielska-Kasprzak, P. Chudoba et al., “Type of renal replacement therapy (hemodialysis versus peritoneal dialysis) does not affect cytokine gene expression or clinical parameters of renal transplant candidates,” BioMed Research International, vol. 2015, Article ID 797490, 7 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Chonchol, “Neutrophil dysfunction and infection risk in end-stage renal disease,” Seminars in Dialysis, vol. 19, no. 4, pp. 291–296, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. L. Butani, J. Johnson, C. Troppmann, J. McVicar, and R. V. Perez, “Predictive value of pretransplant inflammatory markers in renal allograft survival and rejection in children,” Transplantation Proceedings, vol. 37, no. 2, pp. 679–681, 2005. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Varagunam, H. Finney, R. Trevitt et al., “Pretransplantation levels of C-reactive protein predict all-cause and cardiovascular mortality, but not graft outcome, in kidney transplant recipients,” American Journal of Kidney Diseases, vol. 43, no. 3, pp. 502–507, 2004. View at Publisher · View at Google Scholar · View at Scopus
  25. E. M. Simmons, A. Langone, M. T. Sezer et al., “Effect of renal transplantation on biomarkers of inflammation and oxidative stress in end-stage renal disease patients,” Transplantation, vol. 79, no. 8, pp. 914–919, 2005. View at Publisher · View at Google Scholar · View at Scopus
  26. D. J. Tancredi and L. Butani, “Pretransplant serum albumin is an independent predictor of graft failure in pediatric renal transplant recipients,” Journal of Pediatrics, vol. 164, no. 3, pp. 602–606, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Gupta, N. Mitra, P. A. Kanetsky et al., “Association between albuminuria, kidney function, and inflammatory biomarker profile in CKD in CRIC,” Clinical journal of the American Society of Nephrology, vol. 7, no. 12, pp. 1938–1946, 2012. View at Publisher · View at Google Scholar · View at Scopus
  28. K. Kalantar-Zadeh, J. D. Kopple, G. Block, and M. H. Humphreys, “A malnutrition-inflammation score is correlated with morbidity and mortality in maintenance hemodialysis patients,” American Journal of Kidney Diseases, vol. 38, no. 6, pp. 1251–1263, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. I. Beberashvili, A. Azar, I. Sinuani et al., “Objective Score of Nutrition on Dialysis (OSND) as an alternative for the malnutrition-inflammation score in assessment of nutritional risk of haemodialysis patients,” Nephrology Dialysis Transplantation, vol. 25, no. 8, pp. 2662–2671, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. M. M. Abou-Jaoude, N. Nawfal, R. Najm, M. Honeidi, J. Shaheen, and W. Y. Almawi, “Effect of pretransplantation body mass index on allograft function and patient survival after renal transplantation,” Transplantation Proceedings, vol. 42, no. 3, pp. 785–788, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. Y. Lebranchu, C. Baan, L. Biancone et al., “Pretransplant identification of acute rejection risk following kidney transplantation,” Transplant International, vol. 27, no. 2, pp. 129–138, 2014. View at Publisher · View at Google Scholar · View at Scopus
  32. N. N. Massarweh, J. L. Clayton, C. A. Mangum, S. S. Florman, and D. P. Slakey, “High body mass index and short- and long-term renal allograft survival in adults,” Transplantation, vol. 80, no. 10, pp. 1430–1434, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. A. Weissenbacher, M. Jara, H. Ulmer et al., “Recipient and donor body mass index as important risk factors for delayed kidney graft function,” Transplantation, vol. 93, no. 5, pp. 524–529, 2012. View at Publisher · View at Google Scholar · View at Scopus
  34. F. Oppenheimer, P. Aljama, C. Asensio Peinado, J. Bustamante Bustamante, J. F. Crespo Albiach, and L. Guirado Perich, “The impact of donor age on the results of renal transplantation,” Nephrology Dialysis Transplantation, vol. 19, supplement 3, pp. iii11–iii15, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. A. Reutzel-Selke, A. Jurisch, C. Denecke et al., “Donor age intensifies the early immune response after transplantation,” Kidney International, vol. 71, no. 7, pp. 629–636, 2007. View at Publisher · View at Google Scholar · View at Scopus
  36. J. Pratschke, V. Merk, A. Reutzel-Selke et al., “Potent early immune response after kidney transplantation in patients of the European senior transplant program,” Transplantation, vol. 87, no. 7, pp. 992–1000, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. D. E. Hricik, E. D. Poggio, K. J. Woodside et al., “Effects of cellular sensitization and donor age on acute rejection and graft function after deceased-donor kidney transplantation,” Transplantation, vol. 95, no. 10, pp. 1254–1258, 2013. View at Publisher · View at Google Scholar · View at Scopus
  38. J. Hein, U. Schellenberg, G. Bein, and H. Hackstein, “Quantification of murine IFN-γ mRNA and protein expression: impact of real-time kinetic RT-PCR using SYBR green I dye,” Scandinavian Journal of Immunology, vol. 54, no. 3, pp. 285–291, 2001. View at Publisher · View at Google Scholar · View at Scopus
  39. M. Mohammadnia, G. Solgi, M. Ranjbar et al., “Serum levels of interleukin (IL)-10, IL-17, transforming growth factor (TGF)-β1, and interferon-γ cytokines and expression levels of IL-10 and TGF-β1 genes in renal allograft recipients after donor bone marrow cell infusion,” Transplantation Proceedings, vol. 43, no. 2, pp. 495–499, 2011. View at Publisher · View at Google Scholar · View at Scopus