Pretransplant Immune- and Apoptosis-Related Gene Expression Is Associated with Kidney Allograft Function
Table 5
Correlation of gene expression and pretransplant clinical parameters with GFR—simple and multiple linear regression analysis.
Simple regression
Multiple regression
Corr. coeff.
P
Corr. coeff
P
14-day GFR
Recipient age
−0.33
0.003
−0.27
0.012
Donor age
−0.33
0.004
−0.29
0.008
TGFB1
−0.24
0.039
−0.25
0.016
1-month GFR
Recipient age
−0.37
0.001
−0.29
0.005
Donor age
−0.41
0.000
−0.34
0.001
3-month GFR
Recipient age
−0.31
0.010
−0.18
0.176
Donor age
−0.44
0.000
−0.29
0.028
BMI
−0.35
0.009
−0.26
0.065
LCN2
−0.27
0.024
−0.15
0.256
6-month GFR
Recipient age
−0.39
0.001
−0.27
0.018
Donor age
−0.60
0.000
−0.40
0.000
BMI
−0.36
0.010
−0.38
0.001
CASP3
0.27
0.027
0.20
0.072
FAS
0.28
0.021
0.09
0.405
IFNG
0.27
0.029
0.32
0.003
12-month GFR
Recipient age
−0.33
0.008
−0.22
0.047
Donor age
−0.48
0.000
−0.42
0.000
CASP3
0.30
0.016
0.23
0.038
IFNG
0.30
0.018
0.23
0.034
24-month GFR
Recipient age
−0.35
0.012
−0.20
0.082
Donor age
−0.55
0.000
−0.50
0.000
CASP3
0.41
0.003
0.34
0.003
FAS
0.30
0.033
0.23
0.046
IFNG
0.29
0.040
0.20
0.086
IL-18
0.28
0.044
0.23
0.047
Correlation coefficient for a clinical parameter was corrected for other clinical parameters and all listed genes influencing GFR at a given time point; each gene expression was corrected for all clinical parameters influencing GFR at a given time point.
