Research Article

Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis

Figure 4

IL-29-induced cytokine expression by OA synovial fibroblasts. mRNA levels of IL-1β (a), IL-6 (b), IL-8 (c), and MMP-3 (d) in OA FLS after exposure to IL-29 (1, 10, and 100 ng/mL) with or without its blocking antibody for 48 h were determined by real-time PCR. The results shown are representative of one of three independent experiments. The error bars represent mean ± SEM for triplicate wells. versus medium control. versus IL-29 (100 ng/mL) treatment group.
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