Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis

Figure 1

Delayed development of EAE symptoms without change in the severity of the disease in mMCP-4 KO mice. (a) Clinical score of WT (•) or mMCP-4 KO (▪) mice. (b) Sum of clinical score at different set points after immunization of WT (closed bars) and mMCP-4 KO (opened bars) mice. Each point or bar represents the mean ± SEM of 12 (weeks 1 to 3) and 7 mice (4th week). , .

(a)

(b)