Research Article

Syk Plays a Critical Role in the Expression and Activation of IRAK1 in LPS-Treated Macrophages

Figure 3

Syk impacts the transcriptional regulation of IRAK1 in LPS-treated RAW264.7 cells. (a and b) IRAK1 mRNA levels from RAW264.7-WT or RAW264.7-Syk−/− cells with or without LPS (1 μg/ml) treatment, as determined by real-time PCR. (c) IRAK1 mRNA levels from HEK293 cells transfected with Syk, as determined by real-time PCR. All data are expressed as the mean ± SD of three independent replicate experiments. and compared to the control group (LPS alone) or normal group.
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