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Mediators of Inflammation
Volume 2017, Article ID 2582745, 10 pages
Research Article

Statins Reduce Lipopolysaccharide-Induced Cytokine and Inflammatory Mediator Release in an In Vitro Model of Microglial-Like Cells

1Menzies Health Institute Queensland, Griffith University, Gold Coast, QLD, Australia
2School of Pharmacy, Griffith University, Gold Coast, QLD, Australia
3Quality Use of Medicines Network, Gold Coast, QLD 4222, Australia

Correspondence should be addressed to S. Anoopkumar-Dukie; ua.ude.htiffirg@eikud.s

Received 9 October 2016; Revised 15 February 2017; Accepted 13 March 2017; Published 4 May 2017

Academic Editor: Elaine Hatanaka

Copyright © 2017 A. J. McFarland et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure 1. Treatment of differentiated THP-1 cells with FITC-conjugated LPS following statin pre-treatment. Cells were treated with 0.1 μg/mL LPS for 30 minutes, following which cells were washed and fluorescence determined. Data shows mean + SD of three independent experiments.

  1. Supplementary Material