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Mediators of Inflammation
Volume 2017, Article ID 2860956, 7 pages
https://doi.org/10.1155/2017/2860956
Research Article

Epac1 Blocks NLRP3 Inflammasome to Reduce IL-1β in Retinal Endothelial Cells and Mouse Retinal Vasculature

1Department of Anatomy and Cell Biology, Wayne State University School of Medicine, Detroit, MI, USA
2Department of Ophthalmology, Wayne State University School of Medicine, Detroit, MI, USA

Correspondence should be addressed to Jena J. Steinle; ude.enyaw.dem@elnietsj

Received 1 November 2016; Revised 24 January 2017; Accepted 5 February 2017; Published 28 February 2017

Academic Editor: Ulrich Eisel

Copyright © 2017 Youde Jiang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [3 citations]

The following is the list of published articles that have cited the current article.

  • Andrew S. Mendiola, and Astrid E. Cardona, “The IL-1β phenomena in neuroinflammatory diseases,” Journal of Neural Transmission, 2017. View at Publisher · View at Google Scholar
  • Li Liu, Youde Jiang, and Jena J. Steinle, “Epac1 protects the retina against ischemia/reperfusion-induced neuronal and vascular damage,” Plos One, vol. 13, no. 9, pp. e0204346, 2018. View at Publisher · View at Google Scholar
  • Elizabeth Curtiss, Li Liu, and Jena J. Steinle, “miR15a regulates NLRP3 inflammasome proteins in the retinal vasculature,” Experimental Eye Research, 2018. View at Publisher · View at Google Scholar