Epac1 Blocks NLRP3 Inflammasome to Reduce IL-1β in Retinal Endothelial Cells and Mouse Retinal Vasculature

Figure 1

Loss of Epac1 increased TLR4 and cytosolic HMGB1. Western blot data from retinal lysates from Epac1 floxed and Epac1 Cre-Lox mice for TLR4 (a) and cytosolic HMGB1 (b). versus Epac1 floxed. . Data are mean ± SEM.

(a)

(b)