Research Article

Inhibition of Murine Pulmonary Microvascular Endothelial Cell Apoptosis Promotes Recovery of Barrier Function under Septic Conditions

Figure 1

Cytomix induces a dose-dependent increase in mouse PMVEC permeability. PMVEC had significantly higher permeability 4 h after cytomix stimulation by 2 assays: (a) lower transendothelial electrical resistance (TEER) and (b) higher Evans blue- (EB-) labelled albumin flux. Furthermore, by both measures, permeability was maximal at 30 ng/mL cytomix. and represent and 0.01 compared with PBS (one-way ANOVA), respectively. .
(a)
(b)