A Role of the ABCC4 Gene Polymorphism in Airway Inflammation of Asthmatics

Table 2

Distribution of genotypes and haplotypes of ABCC4 gene polymorphisms.

SNP	Genotype	Asthmatics; ()	NC; ()	value
−1508A>G; (rs868853)	AA	224 (83.3)	102 (86.4)	0.288
	AG	47 (17.5)	16 (13.6)	0.417
	GG	2 (0.74)	2 (1.69)	0.648
−642C>G; (rs869951)	CC	94 (34.9)	52 (44.1)	0.61
	CG	139 (51.7)	47 (39.8)	0.101
	GG	36 (13.4)	19 (16.1)	0.068
ht1 [AC]	+/+	94 (34.9)	52 (44.0)	0.171
	+/−	139 (51.7)	47 (39.8)	0.705
	−/−	36 (13.4)	19 (16.1)	0.068
ht2 [AG]	+/+	17 (6.3)	14 (11.9)	0.077
	+/−	156 (57.9)	50 (42.3)	0.094
	−/−	96 (35.7)	54 (45.7)	0.366
ht3 [GG]	+/+	2 (0.74)	2 (1.7)	0.404
	+/−	17 (6.3)	3 (2.5)	0.75
	−/−	250 (92.9)	113 (95.7)	0.454

NC: normal healthy control; n: number of subjects; ht: haplotype. value was obtained by logistic regression analysis with age and sex as covariates.