Table 1: Baseline characteristics of the study populations.

Control ()CKD 3-4 ()CKD 5D () overall (C versus CKD 3-4) (C versus 5D) (CKD 3-4 versus 5D)

Age (years)49 59.5 60.0 <0.0010.001<0.0010.214
Sex
 Man30 (46.2%)27 (61.4%)16 (43.2%)0.189#
 Women35 (53.8%)17 (38.6%)21 (56.8%)
BMI (Kg/m2)24.8 27.8 25.9 0.0100.0130.1300.151
WC (cm)88.6 ± 9.2997.3 ± 12.494.8 ± 10.0<0.001<0.0010.0170.533
Glucose (mg/dL)91.0 100 93.0 0.0090.0040.9280.088
Total cholesterol (mg/dL)183 181 172 0.353#
HDL cholesterol (mg/dL)54.0 50.0 48.0 0.087#
LDL cholesterol (mg/dL)111 ± 23.90109 ± 28.995.3 ± 30.80.0220.8750.0180.095
TG (mg/dL)58 128 108 <0.001<0.001<0.0010.857
SBP (mmHg)121 143 140 <0.001<0.001<0.0010.665
DBP (mmHg)74.7 ± 7.9583.3 ± 10.678.1 ± 12.6<0.001<0.0010.2540.061
CRP (mg/L)0.82 1.38 4.13 <0.0010.099<0.0010.001
25D (ng/mL)25.7 28.1 12.7 <0.0010.556<0.001<0.001
VEGF (pg/mL)233 398 373 0.0020.0040.0130.595

Identified variables with normal distribution. Values of these variables are described with mean ± standard deviation. For variables with significant deviations from normal distribution, values are provided as median [IQR]. Adjusted values in multiple comparisons are not performed for variables with nonsignificant differences according to the overall test ( overall). BMI: body mass index; WC: waist circumference; TG: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; CRP: C-reactive protein; 25D: 25-hydroxyvitamin D; VEGF: Vascular Endothelial Growth Factor.