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Mediators of Inflammation
Volume 2017, Article ID 3827841, 7 pages
https://doi.org/10.1155/2017/3827841
Research Article

Transcriptional Profiling at High Temporal Resolution Reveals Robust Immune/Inflammatory Responses during Rat Sciatic Nerve Recovery

Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China

Correspondence should be addressed to Sheng Yi; nc.ude.utn@iys

Received 2 January 2017; Revised 25 February 2017; Accepted 7 March 2017; Published 12 April 2017

Academic Editor: Vera L. Petricevich

Copyright © 2017 Lingyan Xing et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Additional file 1. List of primer pairs for qRT-PCR; Additional file 2. Diseases and bio functions of DEGs following nerve injury by IPA analysis; Additional file 3. DEGs in immune cell trafficking following injury; Additional file 4. DEGs in inflammatory response following injury; Additional file 5. DEGs in agranulocyte adhesion and diapedesis following injury; Additional file 6. Schematic network of agranulocyte adhesion and diapedesis signaling following injury; Additional file 7. DEGs in granulocyte adhesion and diapedesis following injury; Additional file 8. Schematic network of granulocyte adhesion and diapedesis signaling following injury; Additional file 9. DEGs in IL-6 signaling following injury; Additional file 10. Schematic network of Il-6 signaling following injury; Additional file 11. DEGs in IL-10 signaling following injury; Additional file 12. Schematic network of Il-10 signaling following injury; Additional file 13. Sciatic injury induced DEGs in agranulocyte adhesion and diapedesis; Additional file 14. Sciatic injury induced DEGs in granulocyte adhesion and diapedesis; Additional file 15. Sciatic injury induced DEGs in IL-6 signaling pathway; Additional file 16. Sciatic injury induced DEGs in IL-10 signaling pathway; Additional file 17. Schematic network of agranulocyte/granulocyte adhesion and diapedesis, IL-6 signaling, and IL-10 signaling.

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