15-Deoxy-Δ^12,14-prostaglandin J₂ Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction

Figure 3

Cortical apoptosis and kidney injury are aggravated during UUO by treatment with 15d-PGJ₂. (a) Caspase 3 protein expression. (b) Cleaved caspase 3 (Cl. caspase 3) protein expression. (c) KIM-1 protein expression. Representative blots are shown above each graph. 15d-PGJ₂ was administered at a low (0.5 mg/kg/day) and a high (1 mg/kg/day) dose as depicted in each graph. Data represents mean ± SEM. versus that in sham; versus that in UUO, using ANOVA and Bonferroni’s post hoc tests (, sham; , UUO groups).

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