Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder

Figure 4

Oxylipid metabolites involved in promoting and resolving inflammation that were probed in this study. This schematic depicts oxylipids derived from linoleic acid (a) and α-linolenic acid (b) that were determined in this study. DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; COX, cyclooxygenase; LOX, lipoxygenase; CYP, cytochrome P450 epoxygenase; sEH, soluble epoxide hydrolase; and NE, nonenzymatic. Chemical names of oxylipids are listed in the Materials and Methods.

(a)

(b)