Distinct Signature of Oxylipid Mediators of Inflammation during Infection and Asymptomatic Colonization by E. coli in the Urinary Bladder

Figure 9

LOX pathway-derived oxylipids induced during infection and asymptomatic colonization of the murine urinary tract. Oxylipids in murine urinary bladders were quantified by LC-MS/MS (female CBA/J, ). Mean + SEM are presented here. , ANOVA with Bonferroni’s multiple comparison test. PBS, sham-inoculated control; UPEC, uropathogenic E. coli; ABEC, asymptomatic bacteriuric E. coli; CFT, UPEC strain CFT073; ABU, ABEC strain 83972; h PI, hour postinoculation; HETE, hydroxy eicosatetraenoic acid; HODE, hydroxy octadecadienoic acid; HDoHE, hydroxy docosahexaenoic acid; and DiHDoHE, dihydroxy docosahexaenoic acid.

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