Research Article

Mold Alkaloid Cytochalasin D Modifies the Morphology and Secretion of fMLP-, LPS-, or PMA-Stimulated Neutrophils upon Adhesion to Fibronectin

Figure 3

Effect of cytochalasin D on the external and internal morphology of PMA-treated neutrophils upon adhesion to fibronectin. SEM (a, b) and TEM (c, d) images of neutrophils that were attached to fibronectin-coated substrata over a period of 20 min in the presence of 0,1 μM PMA, taken separately (a, c) or together with 10 μM cytochalasin D (b, d). Pictures represent typical images observed in two independent experiments.