Regulation of Ghrelin Receptor by Periodontal Bacteria In Vitro and In Vivo

Figure 4

(a) GHS-R1a expression in human gingival biopsies from periodontally healthy (H), gingivitis (G), and periodontitis (P) sites, as analyzed by real-time PCR. Mean ± SEM ( donors/group). Significant () difference between groups. (b) GHS-R protein immunostaining in human gingival biopsies from periodontally healthy control and periodontitis sites, as visualized by immunohistochemistry. Representative images from one out of three donors of each group are shown. LP: lamina propria; GE: gingival epithelium. (c) GHS-R1a expression in rat gingival biopsies from periodontally healthy (C) and periodontitis (P) sites at 6 d, 8 d, and 12 d, as analyzed by real-time PCR. Mean ± SEM ( rats/group). Significant () difference between groups.

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