The Role of Defensins in HIV Pathogenesis

Table 2

Cellular sources and tissue localization of selected β-defensins.

	HBD1	HBD2	HBD3	HBD4	HBD5/6	References
Cellular (primary)	Keratinocytes, kidney epithelial cells, airway epithelial cells, female reproductive tract epithelial cells, mammary epithelial cells	Keratinocytes, oral epithelial cells	keratinocytes, airway epithelial cells, oral epithelial cells	Keratinocytes, airway epithelial cells		[28, 75, 128–134]
Cellular (also reported)	Monocytes, macrophages, dendritic cells	Monocytes, macrophages, dendritic cells		Neutrophils
Tissue^a	Pancreas	Trachea, lung	Tonsil, skin	Lung, kidney, uterus, testis, gastric antrum	Epididymis

^amRNA expression was identified in tissues but cellular source was not determined.