IL-10 and socs3 Are Predictive Biomarkers of Dengue Hemorrhagic Fever

Table 2

Potential biomarkers to discriminate healthy from dengue patients.

	AUC	95% CI	value	Cutoff	Sensitivity %	Specificity %
IL-10	0.9683	0.9222–1.014	0.0001	>63.25 pg/ml	90.48	100
IL-6	0.9730	0.9311–1.015	0.0001	>67.77 pg/ml	95.24	100
Platelets	0.9742	0.9362–1.012	0.0001	<13.6 × 10^4/mm^3	93.75	100
Albumin	0.7594	0.5743–0.9245	0.0128	<3.55 UI/ml	78.38	63.64
ALT	0.9315	0.8263–1.037	0.0001	>42.5 UI/ml	83.33	100
AST	0.9167	0.8008–1.032	0.0001	>31.5 UI/ml	88.89	93.75

AUC analysis was done to identify parameters that can discriminate between healthy and sick dengue-infected patients. Sensitivity and specificity values are calculated on the base of the cutoff of each tested parameter.