Clinical Study

A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease

Table 2

Glucometabolic variables according to the randomized groups at baseline and after 3 months. Median (25, 75 percentiles) is given.

ParameterBaseline3 monthsΔp
Saxagliptin ()Placebo ()Saxagliptin ()Placebo ()

HbA1c (%)7.5 (7.1, 8.3)7.3 (6.8, 7.7)6.9 (6.7, 7.4)7.2 (6.9, 7.7)0.017
Glucose (mmol/L)8.2 (7.7, 9.7)8.5 (7.4, 10.6)7.2 (6.5, 10.0)8.5 (7.7, 10.4)0.329
Insulin (pmol/L)72 (55, 139)60 (43, 104)58 (52, 116)71 (38, 119)0.818
C-peptide (pmol/L)1090 (810, 1573)1025 (767, 1345)897 (758, 1599)887 (744, 1649)0.818

 refers to intragroup change in the saxagliptin group, ; Δp refers to difference in changes from baseline to 3 months between the groups.