Suppressed Programmed Death 1 Expression on CD4⁺ and CD8⁺ T Cells in Psoriatic Patients

Table 3

Correlations between clinical data and the distribution of PBMCs and PD-1 expression in the psoriatic patients.

PBMC and PD-1 expression	IU	r	Duration of psoriasis (years)	Age of psoriasis onset (years)	PASI	BSA	IGA	NAPSI 80	DLQI
		p
CD3^+	Cells/μL	r	−0.113	−0.043	−0.279	−0.177	−0.181	−0.260	−0.011
		p	0.335	0.712	0.015	0.130	0.120	0.024	0.924
	%	r	−0.036	−0.030	0.093	0.050	0.057	−0.043	0.136
		p	0.758	0.797	0.429	0.670	0.626	0.717	0.243
CD4^+	Cells/μL	r	−0.120	0.085	−0.373	−0.238	−0.297	−0.231	−0.106
		p	0.307	0.471	0.001	0.040	0.010	0.046	0.367
	%	r	−0.047	0.162	−0.295	−0.205	−0.291	−0.078	−0.159
		p	0.687	0.164	0.010	0.078	0.011	0.508	0.174
CD8^+	Cells/μL	r	0.070	−0.190	0.140	0.106	0.164	−0.084	0.147
		p	0.548	0.102	0.229	0.366	0.161	0.476	0.207
	%	r	0.116	−0.168	0.338	0.253	0.309	0.069	0.154
		p	0.320	0.150	0.003	0.029	0.007	0.559	0.186
CD4^+PD-1^+	Cells/μL	r	−0.117	−0.030	−0.283	−0.129	−0.148	−0.180	−0.018
		p	0.317	0.797	0.014	0.269	0.204	0.122	0.882
	%	r	−0.034	−0.120	−0.114	−0.001	−0.008	0.017	0.026
		p	0.771	0.305	0.330	0.999	0.945	0.884	0.828
CD8^+PD-1^+	Cells/μL	r	−0.035	−0.257	0.023	−0.036	0.090	−0.103	−0.004
		p	0.767	0.026	0.848	0.759	0.445	0.379	0.973
	%	r	−0.029	−0.053	−0.022	−0.061	0.047	−0.042	−0.061
		p	0.804	0.655	0.852	0.601	0.692	0.721	0.601

PASI: Psoriasis Area and Severity Index; BSA: Body Surface Area; IGA: Investigator Global Assessment; DLQI: Dermatology Life Quality Index; NAPSI 80: Nail Psoriasis Severity Index 80; PBMCs: peripheral blood mononuclear cells; PD-1: programmed death 1; cells/μL: number of lymphocytes/μL.