Dengue Virus Induces NK Cell Activation through TRAIL Expression during Infection

Figure 1

NK cell populations’ frequency among dengue-infected patients. Patients’ PBMCs collected during disease acute phase were phenotyped by CD56/CD16 cell surface density analysis by flow cytometry. Graphs represent median values (blue line) for NK subpopulation CD56+CD16− (a) or CD56+CD16+ (b) frequencies among total PBMCs from patients or healthy donors (HD) in which each point represents one subject. Patients were ranked by severity: Dengue fever without warning signs (DF) or with warning signs (DFWS) and severe dengue (SD). Values were submitted to Mann–Whitney statistical test (for comparison between two groups in which) and one-way analysis of variance for linear tendency between group severity and analyzed parameters.

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