Dengue Virus Induces NK Cell Activation through TRAIL Expression during Infection
Table 1
Demographic, clinical, and laboratorial characteristics of DENV infected patients.
Characteristics
DF & DFWS2
(N)
Severe dengue
(N)3
Age (median, 25–75%)
43, 26–58
(33)
42, 24–50
(10)
Gender (M : F)
14 : 19
(31)
5 : 5
(10)
Infecting serotype
DENV-2 positive/tested%
9/33 (27.2%)
(33)
1/10 (10.0%)
(10)
DENV-1 positive/tested%
4/33 (12.1%)
(33)
0/10 (0%)
(10)
Previous dengue infection (IgG positive)
79%
(30)
100%
(8)
Platelet count (×103/mm3)4
121 (82–146.8)
(23)
28 (2.5–77.4) +5
(7)
Hematocrit
42 (39.8–43.6)
(22)
43 (38.4–47)
(7)
Leucocyte count (×103/mm3)
4500 (3442–6218)
(27)
2750 (1737–4270)
(8)
ALT (IU/L)
63 (47.6–140.1)
(23)
159 (54–583) +5
(8)
AST (IU/L)
74.5 (56.8–132)
(23)
145 (115.7–667.7)δ
(9)
Study population ; 2DF (dengue fever without warning signs) and DFWS (dengue fever with warning signs; severe dengue according to [21]); 3number of patients with available data; 4C.I., 95% confidence interval; 5+ represents statistical difference of DF and DFWS versus severe dengue; Mann–Whitney nonparametric test was applied; δ.
