Research Article

Association between Interleukin-10-1082 G/A and Tumor Necrosis Factor- 308 G/A Gene Polymorphisms and Respiratory Distress Syndrome in Iranian Preterm Infants

Table 4

Frequency of genotype or allele of TNF-α-308 and IL-10-1082 polymorphism in different groups of pediatrics.

PolymorphismGenotype/alleleControl ( (%))RDS ( (%))OR (95% CI)

TNF-alpha-308
AA98 (82.4)102 (87.7)0.4790.778 (0.387–1.561)
GA21 (17.6)17 (14.3)
A allele217 (91.2)221 (92.9)0.4990.795 (0.408–1.548)
G allele21 (8.8)17 (7.1)

IL-10-1082GG87 (73.1)69 (58)0.0141.97 (1.143–3.397)
GA32 (26.9)50 (42)
G allele206 (86.6)188 (79)0.0291.712 (1.053–2.783)
A allele32 (13.4)50 (21)

Respiratory distress syndrome.