Prevention of Memory Impairment and Neurotrophic Factors Increased by Lithium in Wistar Rats Submitted to Pneumococcal Meningitis Model

Figure 3

Effects of lithium and tamoxifen on step-down inhibitory avoidance task in adult Wistar rats 10 days after pneumococcal meningitis induction. Data are reported as median and interquartile ranges, and comparisons among groups were performed using Mann–Whitney U tests (). The within-individual groups were analyzed by Wilcoxon’s tests. indicates differences between training and test sessions as determined by Wilcoxon, ^& indicates the statistical significance of the control/saline group as described by Mann–Whitney, and ^# indicates statistical significance of the meningitis/saline group as determined by Mann–Whitney.