Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis

Figure 2

Morphometric analysis of JAK1 (a), JAK2 (b), STAT1 (c), STAT3 (d), and STAT5 (e) immunoexpression in keratinocytes, evaluated with Western blot. The results are presented as % optical density over the background (the mean ± SD). Control—normal skin. DH—dermatitis herpetiformis, skin lesions. BP—bullous pemhigoid, skin lesions. The level of significance is defined where . JAK1: C versus DH (NS), C versus BP (NS), and DH versus BP (NS). JAK2: C versus DH (NS), C versus BP (), and BP versus DH (). STAT1: C versus DH (), C versus BP (), and DH versus BP (NS). STAT3: C versus DH (), C versus BP (), and DH versus BP (). STAT5: C versus DH (), C versus BP (), and DH versus BP (NS).

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