Expression of the JAK/STAT Signaling Pathway in Bullous Pemphigoid and Dermatitis Herpetiformis

Figure 6

Morphometric analysis of JAK3 (a), STAT2 (b), STAT4 (c), and STAT6 (d) immunoexpression in keratinocytes, evaluated with immunohistochemistry. The results of semiquantitative analysis are expressed as the mean ± SD. Control—normal skin. DH—dermatitis herpetiformis, skin lesions. BP—bullous pemphigoid, skin lesions. The level of significance is defined where . JAK3: C versus DH (), C versus BP (), and DH versus BP (NS). STAT2: C versus DH (), C versus BP (), and BP versus DH (NS). STAT4: C versus DH (), C versus BP (), and DH versus BP (). STAT6: C versus DH (), C versus BP (), and DH versus BP (NS).

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