Mediators of Inflammation / 2017 / Article / Tab 1

Research Article

Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk

Table 1

SNPs of IL17A, IL23R, and IL17RA 3-UTRs within miRNA binding sites.

GeneSNPMAFPredicted miRNA bindingΔΔG (kJ/mol)

IL17Ars37480670.13hsa-miR-10a-3p−9.59
IL23Rrs108896770.29hsa-miR-1827−19.12
hsa-miR-5680−10.37
IL17RArs14684880.08hsa-miR-320a−25.44
hsa-miR-320b−21.68
hsa-miR-320c−19.96
hsa-miR-320d−17.64
hsa-miR-320e−16.75
hsa-miR-513c-5p−19.47
hsa-miR-514b-5p−19.52
rs8877960.18hsa-miR-4761-3p−16.16

SNP: single-nucleotide polymorphism; MAF: minor allele frequency.

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