Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways

<div>SQV regulates macrophages in the lung after liver I/R. IHC was used to stain either macrophages (CD11b<sup>+</sup>) or neutrophils (Ly6G<sup>+</sup>) in the lung tissue after SQV treatment (a). As well, the MIP-2 levels in BALF were tested by ELISA (b). I<i>κ</i>B<i>α</i> and p-I<i>κ</i>B<i>α</i> activation of local lung tissue from all groups was assessed by Western blot (c). 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways 

Figure 3 | Saquinavir Ameliorates Liver Warm Ischemia-Reperfusion-Induced Lung Injury via HMGB-1- and P38/JNK-Mediated TLR-4-Dependent Signaling Pathways 