Research Article

Illicium verum Extract and Trans-Anethole Attenuate Ovalbumin-Induced Airway Inflammation via Enhancement of Foxp3+ Regulatory T Cells and Inhibition of Th2 Cytokines in Mice

Figure 3

Effect of Illicium verum extract (IVE) and trans-anethole (AET) on histologic markers of airway inflammation in lung tissue of OVA-induced mice. (a) H&E, M-T, and PAS staining of lung sections from normal and asthmatic mice treated with OVA (control), IVE (200 ng/kg), or AET (20 or 2 mg/kg). Total index number (b) and PAS-positive cell number (c) were quantitated. H&E: Hematoxylin-eosin; M-T: Masson’s trichrome; PAS: periodic acid-Schiff. Results are expressed as mean ± SEM ( mice per group). and indicate statistically significant differences between the asthma control group and drug-treated group.
(a)
(b)
(c)