Table of Contents Author Guidelines Submit a Manuscript
Mediators of Inflammation
Volume 2017, Article ID 7918472, 11 pages
https://doi.org/10.1155/2017/7918472
Research Article

The Correlation between FSTL1 Expression and Airway Remodeling in Asthmatics

1Department of Pulmonary Medicine, Qilu Hospital of Shandong University, Jinan 250012, China
2Department of Pulmonary Medicine-Bronchoscopy Room, Qilu Hospital of Shandong University, Jinan 250012, China

Correspondence should be addressed to Liang Dong; moc.621@6055ld

Received 4 January 2017; Revised 6 April 2017; Accepted 19 June 2017; Published 3 August 2017

Academic Editor: Sandra Helena Penha Oliveira

Copyright © 2017 Yahui Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. H. Broide, “Immunologic and inflammatory mechanisms that drive asthma progression to remodeling,” The Journal of Allergy and Clinical Immunology, vol. 121, pp. 560–570, 2008, quiz 571–572. View at Publisher · View at Google Scholar · View at Scopus
  2. N. Hirota and J. G. Martin, “Mechanisms of airway remodeling,” Chest, vol. 144, pp. 1026–1032, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. T. R. Bai, “Evidence for airway remodeling in chronic asthma,” Current Opinion in Allergy and Clinical Immunology, vol. 10, pp. 82–86, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. L. James, T. R. Bai, T. Mauad et al., “Airway smooth muscle thickness in asthma is related to severity but not duration of asthma,” The European Respiratory Journal, vol. 34, pp. 1040–1045, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Doherty and D. Broide, “Cytokines and growth factors in airway remodeling in asthma,” Current Opinion in Immunology, vol. 19, pp. 676–680, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Shibanuma, J. Mashimo, A. Mita, T. Kuroki, and K. Nose, “Cloning from a mouse osteoblastic cell line of a set of transforming-growth-factor-beta 1-regulated genes, one of which seems to encode a follistatin-related polypeptide,” European Journal of Biochemistry/FEBS, vol. 217, pp. 13–19, 1993. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Zwijsen, H. Blockx, W. Van Arnhem et al., “Characterization of a rat C6 glioma-secreted follistatin-related protein (FRP): cloning and sequence of human homologue,” European Journal of Biochemistry/FEBS, vol. 225, pp. 937–946, 1994. View at Publisher · View at Google Scholar · View at Scopus
  8. C. Kudo-Saito, T. Fuwa, K. Murakami, and Y. Kawakami, “Targeting FSTL1 prevents tumor bone metastasis and consequent immune dysfunction,” Cancer Research, vol. 73, pp. 6185–6193, 2013. View at Publisher · View at Google Scholar
  9. C. Kudo-Saito, “FSTL1 promotes bone metastasis by causing immune dysfunction,” Oncoimmunology, vol. 2, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. K.-C. Li, F. Wang, Y.-Q. Zhong et al., “Reduction of follistatin-like 1 in primary afferent neurons contributes to neuropathic pain hypersensitivity,” Cell Research, vol. 21, pp. 697–699, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Fan, H. Sun, Y. Wang et al., “Follistatin-like 1: a potential mediator of inflammation in obesity,” Mediators of Inflammation, vol. 2013, Article ID 752519, 12 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Wu, Y. Dong, X. Teng, M. Cheng, Z. Shen, and W. Chen, “Follistatin-like 1 attenuates differentiation and survival of erythroid cells through Smad2/3 signaling,” Biochemical and Biophysical Research Communications, vol. 466, pp. 711–716, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. Y. Geng, Y. Dong, M. Yu et al., “Follistatin-like 1 (FSTL1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, pp. 7058–7063, 2011. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Sylva, V. S. Li, A. A. Buffing et al., “The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis,” PLoS One, vol. 6, no. 8, article e22616, 2011. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Xu, X. Qi, J. Gong et al., “Fstl1 antagonizes BMP signaling and regulates ureter development,” PLoS One, vol. 7, no. 4, article e32554, 2012. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Yang, J. Liu, H. Mao, Y. A. Hu, Y. Yan, and C. Zhao, “The expression pattern of follistatin-like 1 in mouse central nervous system development,” Gene Expression Patterns, vol. 9, pp. 532–540, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. K.-C. Li, F.-X. Zhang, C.-L. Li et al., “Follistatin-like 1 suppresses sensory afferent transmission by activating Na+,K+-ATPase,” Neuron, vol. 69, pp. 974–987, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Chaly, A. D. Marinov, L. Oxburgh, D. S. Bushnell, and R. Hirsch, “FSTL1 promotes arthritis in mice by enhancing inflammatory cytokine/chemokine expression,” Arthritis & Rheumatology, vol. 64, pp. 1082–10888, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. Y. Chaly, H. C. Blair, S. M. Smith et al., “Follistatin-like protein 1 regulates chondrocyte proliferation and chondrogenic differentiation of mesenchymal stem cells,” Annals of the Rheumatic Diseases, vol. 74, pp. 1467–1473, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. Chaly, Y. Fu, A. Marinov et al., “Follistatin-like protein 1 enhances NLRP3 inflammasome-mediated IL-1β secretion from monocytes and macrophages,” European Journal of Immunology, vol. 44, pp. 1467–1479, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. S. Maruyama, K. Nakamuram, K. N. Papanicolaou et al., “Follistatin-like 1 promotes cardiac fibroblast activation and protects the heart from rupture,” EMBO Molecular Medicine, vol. 8, pp. 987–1113, 2016. View at Publisher · View at Google Scholar · View at Scopus
  22. M. Shimano, N. Ouchi, K. Nakamura et al., “Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload,” Proceedings of the National Academy of Sciences, vol. 108, pp. E899–E906, 2011. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. Ogura, N. Ouchi, K. Ohashi et al., “Therapeutic impact of follistatin-like 1 on myocardial ischemic injury in preclinical models,” Circulation, vol. 126, pp. 1728–1738, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. X. Li, Y. Fang, X. Li et al., “Apical secretion of FSTL1 in the respiratory epithelium for normal lung development,” PLoS One, vol. 11, no. 6, article e0158385, 2016. View at Publisher · View at Google Scholar · View at Scopus
  25. M. Sylva, V. S. Li, A. A. Buffing et al., “The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis,” PLoS One, vol. 6, no. 8, article e22616, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. K. Bae, K. E. Park, J. Han, J. Kim, K. Kim, and K.-A. Yoon, “Mitotic cell death caused by follistatin-like 1 inhibition is associated with up-regulated Bim inactivated Erk1/2 in human lung cancer cells,” Oncotarget, vol. 7, 2016. View at Publisher · View at Google Scholar · View at Scopus
  27. Y. Dong, Y. Geng, L. Li et al., “Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice,” The Journal of Experimental Medicine, vol. 212, pp. 235–252, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Miller, A. Beppu, P. Rosenthal et al., “FSTL1 promotes asthmatic airway remodeling by inducing oncostatin,” Journal of Immunology, vol. 195, pp. 3546–3556, 2015. View at Publisher · View at Google Scholar · View at Scopus
  29. M. R. Miller, J. A. Hankinson, V. Brusasco et al., “Standardisation of spirometry,” The European Respiratory Journal, vol. 26, no. 2, pp. 319–338, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. P. G. Woodruff and J. V. Fahy, “Airway remodeling in asthma,” Seminars in Respiratory and Critical Care Medicine, vol. 23, pp. 361–367, 2002. View at Publisher · View at Google Scholar · View at Scopus
  31. W. R. Roche, J. H. Williams, R. Beasley, and S. T. Holgate, “Subepithelial fibrosis in the bronchi of asthmatics,” Lancet, vol. 333, pp. 520–524, 1989. View at Publisher · View at Google Scholar · View at Scopus
  32. Y. Chaly, B. Hostager, S. Smith, and R. Hirsch, “Follistatin-like protein 1 and its role in inflammation and inflammatory diseases,” Immunologic Research, vol. 59, no. 1–3, pp. 266–272, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. M. Masoli, D. Fabian, S. Holt, and R. Beasley, “The global burden of asthma: executive summary of GINA dissemination committee report,” Allergy, vol. 59, pp. 468–478, 2004. View at Publisher · View at Google Scholar · View at Scopus