Potential Biomarkers for NSAID-Exacerbated Respiratory Disease

Table 2

Cellular and cytokine markers.

	Mediators and parameters	Biologic sample	Detection method	Baseline		Response after aspirin provocation
				Compared to ATA	Reference	Compared to ATA	Reference
Cell	Eosinophil	NALF	Morphological count of stained slide			↑	[52]
	Platelet-adherent leukocyte	blood	Flow cytometry	↑	[65]
	Soluble platelet surface marker	blood	Immunoassay	↑	[64]
Others	ECP	NALF	Immunoassay			↑	[27]
	Periostin	Blood	Immunoassay	↑	[57]

ATA: aspirin-tolerant asthma; NALF: nasal lavage fluid; ECP: eosinophil cationic protein.