Helminth Products Potently Modulate Experimental Autoimmune Encephalomyelitis by Downregulating Neuroinflammation and Promoting a Suppressive Microenvironment

Figure 4

TcES induce deep changes in the systemic cytokine milieu. Splenocytes from the TcES-treated mice produce different levels of inflammatory (IL-17A, TNF-α) or anti-inflammatory (IL-4, IL-10) cytokines in response to polyclonal (a) or antigen-specific (b) stimuli. The data shown are representative of 2 independent experiments where . Statistical significance between groups was determined by two-tailed Student t-test, , , and .

(a)

(b)