Helminth Products Potently Modulate Experimental Autoimmune Encephalomyelitis by Downregulating Neuroinflammation and Promoting a Suppressive Microenvironment
TcES induce deep changes in the systemic cytokine milieu. Splenocytes from the TcES-treated mice produce different levels of inflammatory (IL-17A, TNF-α) or anti-inflammatory (IL-4, IL-10) cytokines in response to polyclonal (a) or antigen-specific (b) stimuli. The data shown are representative of 2 independent experiments where . Statistical significance between groups was determined by two-tailed Student t-test, , , and .
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