Helminth Products Potently Modulate Experimental Autoimmune Encephalomyelitis by Downregulating Neuroinflammation and Promoting a Suppressive Microenvironment

Figure 5

TcES withdrawal reduces treatment efficacy. All treatments started at disease onset (±day 13 PI) and continued until sacrifice (day 27 PI), but the treatment was suspended on day 19 PI (red arrow) for the EAE + TcES-W group. The data shown are representative of 2 independent experiments. Means and SEM were calculated for a group of mice. The statistical significance between groups was determined by a two-way ANOVA test of the CDI and AUC, and .