Research Article

κ-Carrageenan Enhances Lipopolysaccharide-Induced Interleukin-8 Secretion by Stimulating the Bcl10-NF-κB Pathway in HT-29 Cells and Aggravates C. freundii-Induced Inflammation in Mice

Figure 4

κ-Carrageenan potentiates the LPS-stimulated activation of NF-κB. (a) The effect of κ-carrageenan on the expression of Bcl10, NF-κB, and p-IκBα in HT-29 cells. (b) κ-Carrageenan enhances the LPS-stimulated secretion of Bcl10, NF-κB, and p-IκBα. HT-29 cells were treated with κ-carrageenan for 1 h. (c) κ-Carrageenan induces transcriptional activation of NF-κB. , , compared with the blank group. , , compared with the LPS treated alone.
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