Table 2: Characteristics of studies examining the role of IAP in human IBD.

ReferenceSampleOutcome

Molnár et al., 2012 [28]CD, 10 children (7 boys, 3 girls)
UC, 5 children
(3 boys, 2 girls)
Control, 10 children (5 boys, 5 girls;)
Significantly decreased IAP levels in inflamed mucosa in children with IBD.

Tuin et al., 2009 [19]CD, 10 (3 males, 7 females)
UC, 14 (9 males, 5 females)
Control, 14 (8 males, 6 females)
Reduced IAP mRNA expression in inflamed mucosa in adults with UC and CD.

Lukas et al., 2010 [29]UC, 23 femalesImprovement in disease activity scores,
with clinical effects being observed within 21 days and associated with reductions in C-reactive protein and stool calprotectin.