The Role of Intestinal Alkaline Phosphatase in Inflammatory Disorders of Gastrointestinal Tract

Table 2

Characteristics of studies examining the role of IAP in human IBD.

Reference	Sample	Outcome
Molnár et al., 2012 [28]	CD, 10 children (7 boys, 3 girls); UC, 5 children; (3 boys, 2 girls); Control, 10 children (5 boys, 5 girls;)	Significantly decreased IAP levels in inflamed mucosa in children with IBD.
Tuin et al., 2009 [19]	CD, 10 (3 males, 7 females); UC, 14 (9 males, 5 females); Control, 14 (8 males, 6 females)	Reduced IAP mRNA expression in inflamed mucosa in adults with UC and CD.
Lukas et al., 2010 [29]	UC, 23 females	Improvement in disease activity scores,; with clinical effects being observed within 21 days and associated with reductions in C-reactive protein and stool calprotectin.