Research Article

High Fat Diet Alters Gut Microbiota and the Expression of Paneth Cell-Antimicrobial Peptides Preceding Changes of Circulating Inflammatory Cytokines

Figure 5

Effect of high fat diet consumption on the relative expression of inflammatory cytokines in the small intestinal epithelial cells. Among the 4 cytokines examined, except for IFNγ, the mRNA expressions of TNF-α, IL-1β, and IL-6 were significantly enhanced at least in one of the three HF groups when compared to the control group fed with a LF diet for 8 weeks.