| | Protease | Domain | Cell type | Substrate or interaction partner | Process | References |
| | ADAM7 | D | Lymphocytes | , , | Adhesion | [133] | | ADAM8 | ? | T cells, eosinophils, dendritic cells, monocytes | ? | Migration | [105, 106, 134] | | un | ? | Leukocytes | αL upregulation | Migration | Unpublished | | | MP | Leukocytes | PSGL-1 | Adhesion, migration | [101, 103] | | ADAM9 | D | Neutrophils | , | Migration | [111] | | ADAM10 | MP | Myeloid cells, hematopoietic stem cells | c-met | Migration (ECM degradation) | [96] | | | MP | Neutrophils | CD44 | Migration (ECM interaction) | [94] | | | indirect; MP | Mast cells | Collagen IV | SCF-induced migration | [135] | | | MP | Monocytes | CX3CL1 | Chemotaxis | [74] | | | MP | Neutrophils/monocytes/lymphocytes | DDR1 | Migration (pseudopod extension) | [95] | | | MP | Neutrophils/monocytes | EGFR ligands | Migration | [91] | | | MP | Monocytes | Meprin A | Migration (ECM degradation) | [75, 77] | | | MP | Monocytes | Meprin B | Migration (ECM degradation) | [76] | | | MP | Neutrophils | RAGE | Negative regulation of adhesion/spreading/migration | [81, 82] | | | MP and/or D | Leukocytes | , basement membrane interaction, cytoskeletal rearrangement | Adhesion and migration | [91, 130] | | ADAM17 | MP | Monocytes, lymphocytes | ALCAM | Reduced extravasation (loss of adhesion) | [83–85] | | | MP | Neutrophils | CD44 | Migration (ECM interaction) | [94] | | | MP | Monocytes | CX3CL1 | Chemotaxis | [74] | | | MP | Neutrophils | CXCR2 | Reduction of recruitment | [89] | | | MP | B lymphocytes | Jagged-1/Delta-like 4/Notch | Migration | [92] | | | MP | Neutrophils | L-selectin | Rolling, reduction of transmigration (higher velocity, reduced adhesion), resolution of transmigration | [87, 88, 136] | | | MP | Monocytes | Mac-1 | End of transmigration | [86] | | | MP | Langerhans cells, lymphocytes | TNFR1 | Migration | [97, 137] | | ADAM28 | D | Lymphocytes | , , | Adhesion | [133] | | ADAM33 | D | Lymphocytes | | Adhesion | [133] |
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