Are Thyroid Autoimmune Diseases Associated with Cardiometabolic Risks in a Population with Normal Thyroid-Stimulating Hormone?
Table 2
Associations of AITD with cardiometabolic risk factors by linear regression.
Men
Women
TPO/TgAb (+)
TPO/TgAb and US (+)
TPO/TgAb (+)
TPO/TgAb and US (+)
(95% CI)
(95% CI)
(95% CI)
(95% CI)
BMI
0.171 (−0.186, 0.527)
0.349
0.918 (0.331, 1.504)
0.002
0.353 (0.112, 0.595)
0.004
0.779 (0.456, 1.102)
<0.001
WC
0.097 (−0.925, 1.120)
0.852
1.998 (0.321, 3.674)
0.020
0.712 (0.086, 1.339)
0.026
2.100 (1.263, 2.936)
<0.001
HDL
−0.004 (−0.037, 0.028)
0.792
0.011 (−0.042, 0.064)
0.691
0.001 (−0.021, 0.022)
0.950
−0.004 (−0.033, 0.024)
0.778
LDL
−0.004 (−0.046, 0.006)
0.924
0.021 (−0.107, 0.149)
0.749
0.026 (−0.026, 0.078)
0.331
−0.011 (−0.081, 0.059)
0.751
TC
−0.030 (−0.150, 0.090)
0.625
0.066 (−0.130, 0.262)
0.508
−0.017 (−0.092, 0.059)
0.662
−0.020 (−0.121, 0.081)
0.700
TG
−0.033 (−0.092, 0.027)
0.281
−0.021 (−0.119,0.076)
0.667
0.032 (0.000, 0.065)
0.052
0.035 (−0.009, 0.078)
0.121
HbA1c
−0.014 (−0.030, 0.002)
0.093
−0.004 (−0.030, 0.023)
0.785
0.010 (0.001, 0.019)
0.032
0.011(−0.002, 0.023)
0.089
FPG
−0.021 (−0.042, 0.000)
0.055
0.006 (−0.028, 0.041)
0.724
−0.005 (−0.017, 0.007)
0.444
0.003 (−0.013, 0.019)
0.718
HOMA-IR
−0.011 (−0.083, 0.062)
0.771
0.058 (−0.061, 0.177)
0.340
0.032 (−0.013, 0.077)
0.159
0.071 (0.010, 0.132)
0.021
Systolic BP
−1.509 (−3.536, 0.519)
0.145
−1.071 (−4.418, 2.276)
0.531
0.173 (−1.159, 1.505)
0.799
−0.309 (−2.091, 1.474)
0.731
TG, HbA1c, FPG, and HOMA-IR was ln transformed for normal distribution. The regression models were adjusted for age, smoking history (including current and past), TSH, BMI (not included for BMI and WC in regression model), and menopause status in women.
