Research Article

Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease

Table 1

Clinical characteristics, blood count, and biochemical characteristics of the control group and PAD patients.

Control ()PAD () value

BMI (kg/m2)24 (22.5–25.3)25 (22.5–28)0.021
Diabetes (%)64.1<0.001
Hypertension (%)69.2<0.001
Dyslipidemia37.9<0.001
Red blood cells, ×1012/l4.9 (4.4–5.2)4.16 (3.57–4.66)<0.001
Hemoglobin, mmol/l8.94 (8.32–9.43)13.30 (11.50–14.90)0.001
Leukocytes, ×109/l6.8 (5.4–8.2)8.17 (6.50–10.22)0.003
Platelets, ×109/l233 (205–273)253 (200–329)ns
Total cholesterol, mmol/l4.85 (4.40–5.85)3.90 (3.31–4.94)<0.001
HDL cholesterol, mmol/l1.34 (1.14–1.61)0.96 (0.78–1.19)<0.001
LDL cholesterol, mmol/l2.82 (2.40–3.86)2.26 (1.77–2.79)<0.001
Triglycerides, mmol/l0.90 (0.70–1.38)1.99 (1.40–3.08)<0.001
Glucose, mmol/l4.70 (4.37–4.92)5.61 (4.60–6.88)<0.001
ALT, U/l20 (13.5–24.9)21.5 (15–34.8)ns
AST, U/l20 (17.7–24)21 (16–32)ns

BMI: Body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein; ALT: alanine aminotransferase; AST: aspartate aminotransferase; ns: not significant. Nonparametric variables are shown as medians, and IQR are in parentheses. Qualitative variables are expressed as percentage of total participants.