Plasma Energy-Balance Metabolites Discriminate Asymptomatic Patients with Peripheral Artery Disease

Table 4

Metabolite concentrations in patients segregated according to the presence of hypertension.

Metabolite	Hypertension
	No	Yes
3-hydroxybutirate	0.21 (0.14–0.38)	0.35 (0.14–0.42)
Aconitate	4.59 (2.54–6.65)	4.13 (2.60–6.60)
α-Ketoglutarate	4.71 (2.81–6.67)	3.70 (2.51–7.07)
Alanine	213.5 (152.7–273.7)	184.3 (137.3–255.1)
Aspartate	181.6 (141.4–239.5)	173.1 (137.3–200.4)
(Iso)citrate	721.8 (566.6–934.0)	654.2 (476.5–815.9)
Fumarate	0.27 (0.19–0.40)	0.22 (0.17–0.30)^a
Glucose	4955.9 (4459.1–5679.9)	4418.1 (4134.8–5191.7)^b
Glutamate	1335.8 (725.0–2628.5)	1786.6 (691.1–2891.7)
Glutamine	5083.3 (2842.0–9072.2)	4742.5 (1700.9–7003.8)
Isoleucine	63.52 (52.24–75.19)	57.88 (51.23–63.22)^a
Lactate	373.5 (308.3–452.5)	332.3 (279.5–405.9)^a
Leucine	90.17 (71.33–109.35)	84.54 (69.77–93.84)
Malate	2.79 (1.96–4.09)	2.23 (1.75–3.08)^a
Pyruvate	13.86 (3.85–24.11)	8.78 (2.72–18.15)^a
Serine	135.3 (106.1–162.1)	161.0 (103.6–172.0)^a
Succinate	9.15 (8.42–15.04)	11.71 (8.49–15.47)
Succinyl-CoA	11.21 (7.72–16.31)	9.94 (7.52–14.25)
Valine	107.3 (86.6–136.8)	96.6 (78.8–134.8)

^a; ^b.