Oxysterols Increase Inflammation, Lipid Marker Levels and Reflect Accelerated Endothelial Dysfunction in Experimental Animals

Table 1

Results of ANOVA analysis of parameters between groups and inside each group (between first and last sampling).

Parameter

Body mass

Total cholesterol

LDL cholesterol

HDL cholesterol

HDL cholesterol as percent of total cholesterol

Triacylglycerols

tHCY

ADMA

PON-1

IL-6

TNF-α

CRP

Differences between groups for all sampling ( values)

C–ECh

<0.05

<0.001

<0.001

<0.01

<0.001

<0.05

<0.001

<0.001

NS

<0.001

<0.001

<0.001

C–Ch

NS

<0.001

<0.001

<0.001

<0.001

<0.05

<0.05

<0001

<0.01

<0.001

<0.001

<0.001

ECh–Ch

NS

<0.001

<0.001

<0.01

NS

NS

<0.01

<0.001

NS

<0.001

<0.001

NS

Differences inside each group between 0 day and 180 day ( values)

Ech

<0.001

<0.001

<0.001

<0.01

<0.001

NS

<0.001

<0.001

<0.001

<0.001

<0.001

<0.001

Ch

<0.001

<0.001

<0.001

<0.001

<0.001

NS

<0.001

<0.001

<0.001

<0.05

<0.001

<0.001

C

<0.001

NS

NS

NS

NS

<0.001

NS

NS

NS

NS

NS

NS

NS: nonstatistically significant.