Elevated Expression of AXL May Contribute to the Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Patients

Figure 2

Distinct expression of genes and microRNA regulating epithelial-to-mesenchymal transition in IBD patients. The relative gene expression of TAM receptors TYRO3 (a), AXL (b), and MERTK (c); their receptors GAS6 (d) and PROS1 (e); and genes involved in epithelial-to-mesenchymal transition SNAI1 (f), ZEB2 (g), MMP9 (h), CDH1 (i), VIM (j), and HIF1α (k) as well as microRNA miR-192 (l) are shown from inactive (left, ), active-uninflamed (middle, ), and active-inflamed (right, ) colon samples of IBD patients. Dots and lines represent individual values and the mean, respectively; .

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