GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway

<div>Liraglutide attenuated pulmonary inflammation and pulmonary edema in LPS-induced ALI. (a) After 72 h of intervention, mice were sacrificed and their right lower lungs were fixed. The tissue sections were then stained with H&amp;E. The figure demonstrates a representative view (×200) from each group. (b) Severity of lung injury was measured by the lung injury scoring system. (c) The left lower lungs were obtained to evaluate the W/D ratio of the lung tissues. (d) MPO activity was measured to evaluate the accumulation and activation of neutrophils in the lung tissues. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: GLP-1 Analogue Liraglutide Enhances SP-A Expression in LPS-Induced Acute Lung Injury through the TTF-1 Signaling Pathway 