Clinical Study

Plasma Cytokine Levels in Fibromyalgia and Their Response to 15 Weeks of Progressive Resistance Exercise or Relaxation Therapy

Table 4

Change in clinical and functional measures after interventions in women with fibromyalgia.

ExerciseRelaxation
BeforeΔBeforeΔ

VAS global pain intensity (0–100)50.0 (36.0)−16.0 (40.0)56.0 (26.0)2.0 (18.0)
PPT (kPa)178.6 (±77.1)7.3 (±67.0)183.1 (±88.7)−15.9(±46.9)
Hand grip force (N)196.2 (±70.9)21.0 (±40.0)177.6 (±72.5)20.3 (±46.0)
Elbow flexion force (kg)12.4 (±4.9)2.1 (±3.1)11.1 (±5.3)1.3 (±3.6)
Knee extension force (N)321.6 (±108.2)29.3(±69.3)295.3 (±111.9)−3.0 (±68.6)
6MWT (m)565.4 (±75.4)17.3 (±63.1)542.0 (±67.4)−4.6 (±44.2)
PDI (0–70)38.0 (17.0)−5.0 (13.0)36.0 (15.5)0.0 (11.0)
HADS-depression (0–21)7.0 (5.0)−1.0 (4.0)7.0 (4.0)0.0 (2.0)
HADS-anxiety (0–21)8.0 (6.0)0.0 (5.0)8.0 (6.0)0.0 (3.0)
PCS (0–52)18.0 (16.0)−3.0 (11.0)19.0 (18.5)−2.0 (8.5)
SF36-PSC (0–100)31.2 (9.4)1.7 (11.7)28.5 (10.4)1.3 (6.9)
SF36-MSC (0–100)36.6 (16.6)2.5 (8.6)41.4 (20.2)0.7 (12.0)
FIQ (0–100)57.1 (23.4)−7.1 (15.5)60.9 (26.0)−0.6 (19.9)
MFI (0–20)
 General fatigue19.0 (4.0)−1.0 (3.0)19.0 (3.5)0.0 (1.8)
 Physical fatigue16.0 (4.0)−2.0 (5.3)17.0 (5.0)0.0 (2.0)
 Reduced activity14.0 (6.0)−1.0 (4.3)15.0 (5.5)0.0 (3.0)
 Reduced motivation10.0 (5.0)−1.0 (4.0)9.0 (5.0)0.0 (3.0)
 Mental fatigue16.0 (5.0)−2.0 (4.3)16.0 (6.0)0.0 (3.8)

Data are presented as mean (±SD) or median (interquartile range) before and their change (Δ) after 15 weeks of progressive resistance exercise or relaxation therapy. Note that these data essentially have been published elsewhere [23]. BMI = body mass index; BP = blood pressure; FIQ = fibromyalgia impact questionnaire; HADS = hospital anxiety and depression scale; MFI = multidimensional fatigue inventory; PDI = pain disability index; PPT = pressure pain thresholds (mean of 8 sites); SF36 = Short Form Health Survey 36, physical (PSC) and mental summary components (MSC); 6MWT = 6-min walk test; VAS = visual analogue scale. Italic figures denote significant group difference (independent t-test/Mann–Whitney U test; ).