High-Fat Diet and Alcohol Intake Promotes Inflammation and Impairs Skin Wound Healing in Wistar Rats

Table 2

Effects of alcohol and high-fat diet on serum glucose, triacylglycerol, total cholesterol, HDL cholesterol, AST, and ALT concentrations in Wistar rats.

mg/dL	C1	C2	AL	HF	HF + AL
Glucose	141.6 ± 25.3	144.8 ± 17.1	163.5 ± 23.4	159 ± 13.1	163.1 ± 20.5
Triacylglycerol	25.8 ± 3.9	33.83 ± 6.25	35.7 ± 9.7	37.6 ± 8.2	41.5 ± 11.2^#
Total cholesterol	71.5 ± 12.1	60.1 ± 9.5	78.6 ± 10.6	60.3 ± 12.4	57.1 ± 20.5
HDL cholesterol	25.5 ± 2.9	21.5 ± 1.9	25 ± 3.2	20.1 ± 2.1	24 ± 3.7
AST	123.7 ± 16.4	175 ± 31.6	269 ± 21.4	285 ± 25.4	228 ± 21.6
ALT	23.6 ± 2.1	22.8 ± 1.8	28.3 ± 1.8	29.2 ± 2.9	28.5 ± 2.4

Blood samples were taken after euthanasia (day 61). C1: control, water via gavage and standard chow diet; C2: control, water (no gavage) and standard chow diet; AL: alcohol (40%) via gavage and standard chow diet; HF: water (no gavage) and high-fat diet (50%); HF + AL: alcohol (40%) via gavage and high-fat diet. indicates statistical differences versus C1 and C2; # indicates statistical difference versus C1, C2, AL, and HF.