Research Article

Gamisoyo-San Ameliorates Neuroinflammation in the Spinal Cord of hSOD1G93A Transgenic Mice

Figure 1

GSS administration increases motor neuron survival and modulates inflammation in the spinal cord of hSOD1G93A transgenic (Tg) mice. (a) Representative Western blot showing the expression of SMN (marker of motor neurons), Iba-1 or CD11b (microglia activation markers), and GFAP (astrocyte activation marker) in the spinal cord of control (Non-Tg), hSOD1G93A Tg, and Tg mice treated with GSS (Tg + GSS). GAPDH was used as a loading control. (b) Quantitative analysis of the normalized levels of SMN, Iba-1, GFAP, and CD11b against GAPDH. Data represent the means ± SEM () and were evaluated by one-way ANOVA and Newman-Keuls’ post hoc test. and .
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