Research Article
Activation of GABAB Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn
Figure 3
The development of mechanical allodynia and thermal hyperalgesia in the control, diabetic neuropathic pain (DNP), DNP + baclofen (GABAB receptor agonist), and DNP + saclofen (GABAB receptor blocker) groups at 0, 1, 2, and 3 days after intrathecal administration. (a) The mechanical paw withdrawal threshold (PWT). (b) The paw withdrawal thermal latency (PWTL). Bar graphs represent mean ± SEM. , compared with the DNP group ().
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