Vγ4+ T Cells: A Novel IL-17-Producing γδ T Subsets during the Early Phase of Chlamydial Airway Infection in Mice

<div>Vγ4 cells at day 3 p.i. and Vγ1 cells at day 7 p.i. are the major sources of IFNγ during Cm lung infection. IFNγ+ Vγ1+/Vγ4+ T cells were gated (a). Staining with anti-mouse CD3, TCRγδ, TCRVγ1/Vγ4, and IFNγ/IL-17 antibody to analyze the percentage and absolute number of IFNγ+ Vγ1+ T cells (b) and IFNγ+ Vγ4+ T cells (c) in lung tissues after Cm infection by flow cytometry. Comparison between IFNγ+ Vγ1+ cell and IFNγ+ Vγ4+ cell with its absolute number (d). 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Mediators of Inflammation

fig4

Figure 4

Figure 4: Vγ4+ T Cells: A Novel IL-17-Producing γδ T Subsets during the Early Phase of Chlamydial Airway Infection in Mice